IBUPROFEN IMP C
rac-Ibuprofen amide
CAS: 59512-17-3
Molecular Formula: C13H19NO
IBUPROFEN IMP C - Names and Identifiers
IBUPROFEN IMP C - Physico-chemical Properties
| Molecular Formula | C13H19NO |
| Molar Mass | 205.3 |
| Density | 0.994±0.06 g/cm3(Predicted) |
| Melting Point | 110-114 |
| Boling Point | 356.1±21.0 °C(Predicted) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White |
| BRN | 2448195 |
| pKa | 16.23±0.50(Predicted) |
| Storage Condition | Refrigerator |
IBUPROFEN IMP C - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
| Hazard Note | Irritant |
IBUPROFEN IMP C - Introduction
rac-Ibuprofen (rac-Ibuprofen), also known as ibuprofen amide, is an impurity in the over-the-counter drug ibuprofen. The following is a description of some properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: Usually white crystalline powder.
-Melting point: About 144-147 ° C.
-Solubility: rac-Ibuprofen amide can be dissolved in polar solvents (such as alcohols and chlorinated hydrocarbons), but its solubility in non-polar solvents is low.
Use:
- rac-Ibuprofen is usually used as the target compound for the Study of ibuprofen, used to analyze and detect the content of ibuprofen.
-The compound can also be used as a reference substance for ibuprofen products in the pharmaceutical industry for the purpose of quality control and quality assurance.
Method:
- rac-Ibuprofen can be prepared by reacting ibuprofen with an appropriate amine under suitable conditions. A common preparation method is to react ibuprofen with amine in the presence of sodium carbonate with sodium carbonate crystals or triphosphite as catalyst, heating and stirring in an organic solvent.
Safety Information:
- rac-Ibuprofen the toxicity of amide is limited, its toxicity is generally considered to be low.
-Care should be taken to follow safe practices, such as wearing appropriate personal protective equipment.
-Avoid inhalation, ingestion or contact with skin and eyes.
-If you are exposed or unwell, you should immediately seek medical advice and bring a label or safety data sheet for the relevant substance.
Nature:
-Appearance: Usually white crystalline powder.
-Melting point: About 144-147 ° C.
-Solubility: rac-Ibuprofen amide can be dissolved in polar solvents (such as alcohols and chlorinated hydrocarbons), but its solubility in non-polar solvents is low.
Use:
- rac-Ibuprofen is usually used as the target compound for the Study of ibuprofen, used to analyze and detect the content of ibuprofen.
-The compound can also be used as a reference substance for ibuprofen products in the pharmaceutical industry for the purpose of quality control and quality assurance.
Method:
- rac-Ibuprofen can be prepared by reacting ibuprofen with an appropriate amine under suitable conditions. A common preparation method is to react ibuprofen with amine in the presence of sodium carbonate with sodium carbonate crystals or triphosphite as catalyst, heating and stirring in an organic solvent.
Safety Information:
- rac-Ibuprofen the toxicity of amide is limited, its toxicity is generally considered to be low.
-Care should be taken to follow safe practices, such as wearing appropriate personal protective equipment.
-Avoid inhalation, ingestion or contact with skin and eyes.
-If you are exposed or unwell, you should immediately seek medical advice and bring a label or safety data sheet for the relevant substance.
Last Update：2024-04-09 19:05:56
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Spot supply
Product Name: 2-(4-Isobutylphenyl)propanamide Visit Supplier Webpage Request for quotationCAS: 59512-17-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Rac-Ibuprofen amide Visit Supplier Webpage Request for quotationCAS: 59512-17-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
IBUPROFEN IMP C
N-ALPHA-Z-L-2,4-DIAMINOBUTYRIC ACID
N-(3-乙酰基-4-(2-羟基-3-(异丙基氨基)丙氧基)苯基)乙酰胺
4-METHYLPYRIDINE 1-OXIDE
C.I.Vat Brown 57
2-[2,4-DINITROPHENYLAZO]NAPHTHOL-3,6-DISULFONIC ACID DISODIUM SALT
FMOC-ORN[TRT(4-CH3)]-OH
Silane, (4-chlorophenyl)triethoxy-
2-Propenoic acid, ethyl ester, polymer with N-(hydroxymethyl)-2-propenamide and 2-propenenitrile
N6-[(PHENYLMETHOXY)CARBONYL]-R-LYSINE
N-ALPHA-Z-L-2,4-DIAMINOBUTYRIC ACID
N-(3-乙酰基-4-(2-羟基-3-(异丙基氨基)丙氧基)苯基)乙酰胺
4-METHYLPYRIDINE 1-OXIDE
C.I.Vat Brown 57
2-[2,4-DINITROPHENYLAZO]NAPHTHOL-3,6-DISULFONIC ACID DISODIUM SALT
FMOC-ORN[TRT(4-CH3)]-OH
Silane, (4-chlorophenyl)triethoxy-
2-Propenoic acid, ethyl ester, polymer with N-(hydroxymethyl)-2-propenamide and 2-propenenitrile
N6-[(PHENYLMETHOXY)CARBONYL]-R-LYSINE